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Clinical Trial Design for a Phase II, Randomized Placebo-Controlled Trial of AMX0035 in Alzheimer’s Disease
Lead Author: Kent L. Leslie
Published: Alzheimer’s Association International Conference (AAIC)
Date: July 24, 2018
Efficacy and Pharmacokinetics of Subcutaneous Exendin (9-39) in Patients with Post-Bariatric Hypoglycaemia
Lead Author: Colleen M. Craig, MD
Published: Diabetes, Obesity and Metabolism
Date: February 1, 2018
Clinical Trial Design for a Phase II, Randomized, Placebo-Controlled Trial of AMX0035 in Amyotrophic Lateral Sclerosis (CENTAUR)
Lead Author: Joshua Cohen, Co-CEO and Co-Founder, Amylyx Pharmaceuticals
Published: International Symposium on ALS-MND (MNDA)
Date: December 9, 2017
Evaluation of AMX0035, a Novel Combination Therapy for the Treatment of Neurodegenerative Diseases, in Cellular Models of Friedreich’s Ataxia
Lead Author: Kent L. Leslie
Published: International Ataxia Research Conference
Date: September 29, 2017
AMX0035, a Novel Combination Therapeutic Candidate for Treatment of Primary Mitochondrial Diseases
Lead Author: Kent L. Leslie
Published: United Mitochondrial Disease Foundation Mitochondrial Medicine
Date: June 29, 2017
Critical Role for GLP-1 in Symptomatic Post-Bariatric Hypoglycaemia
Lead Author: Colleen M. Craig, MD
Published: Diabetologia
Date: March 1, 2017
Exendin-(9–39) Corrects Fasting Hypoglycemia in SUR-1–/– Mice by Lowering cAMP in Pancreatic β-Cells and Inhibiting Insulin Secretion
Lead Author: Diva D. De León, MD
Published: Metabolism and Bioenergetics
Date: September 1, 2008
Glucagon-Like Peptide-1 is a Physiological Incretin in Rat
Lead Author: Zhili Wang, PhD
Published: Journal of Clinical Investigation
Date: January 1, 1995
Cloning and Functional Expression of the Human Islet GLP-1 Receptor: Demonstration That Exendin-4 Is an Agonist and Exendin-(9–39) an Antagonist of the Receptor
Lead Author: Bernard Thorens, PhD
Published: Diabetes
Date: November 1, 1993