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Efficacy and Pharmacokinetics of Subcutaneous Exendin (9-39) in Patients with Post-Bariatric Hypoglycaemia

Lead Author: Colleen M. Craig, MD

Published: Diabetes, Obesity and Metabolism

Date: February 1, 2018

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Clinical Trial Design for a Phase II, Randomized, Placebo-Controlled Trial of AMX0035 in Amyotrophic Lateral Sclerosis (CENTAUR)

Lead Author: Joshua Cohen, Co-CEO and Co-Founder, Amylyx Pharmaceuticals

Published: International Symposium on ALS-MND (MNDA)

Date: December 9, 2017

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Evaluation of AMX0035, a Novel Combination Therapy for the Treatment of Neurodegenerative Diseases, in Cellular Models of Friedreich’s Ataxia

Lead Author: Kent L. Leslie

Published: International Ataxia Research Conference

Date: September 29, 2017

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AMX0035, a Novel Combination Therapeutic Candidate for Treatment of Primary Mitochondrial Diseases

Lead Author: Kent L. Leslie

Published:  United Mitochondrial Disease Foundation Mitochondrial Medicine

Date: June 29, 2017

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Critical Role for GLP-1 in Symptomatic Post-Bariatric Hypoglycaemia

Lead Author: Colleen M. Craig, MD

Published: Diabetologia

Date: March 1, 2017

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Exendin-(9–39) Corrects Fasting Hypoglycemia in SUR-1–/– Mice by Lowering cAMP in Pancreatic β-Cells and Inhibiting Insulin Secretion

Lead Author: Diva D. De León, MD

Published: Metabolism and Bioenergetics

Date: September 1, 2008

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Glucagon-Like Peptide-1 is a Physiological Incretin in Rat

Lead Author: Zhili Wang, PhD

Published: Journal of Clinical Investigation

Date: January 1, 1995

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Cloning and Functional Expression of the Human Islet GLP-1 Receptor: Demonstration That Exendin-4 Is an Agonist and Exendin-(9–39) an Antagonist of the Receptor

Lead Author: Bernard Thorens, PhD

Published: Diabetes

Date: November 1, 1993

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